Polynucleotides are at the forefront of regenerative aesthetic medicine, offering a cellular-level approach to skin rejuvenation. At The Grange Clinic, we use Ameela Polynucleotides, a next-generation treatment designed to repair, restore, and elevate overall skin quality.

Ameela Polynucleotides stimulate fibroblast activity, boosting collagen and elastin production, enhancing hydration and elasticity, and supporting natural wound healing. They also soothe inflammation and rebalance melanocyte activity, improving skin tone, texture, and luminosity.

This treatment is especially effective for fine lines, skin laxity, acne scarring, uneven tone, and delicate areas such as the under-eyes. By supporting the skin’s own repair mechanisms and maintaining natural hyaluronic acid levels, Ameela delivers firmer, smoother, and more radiant-looking skin. It can be used alone or alongside other aesthetic procedures for enhanced, natural results.

Ameela Polynucleotides are sourced ethically and sustainably from wild salmon in pristine waters. DNA from these fish has up to 95% similarity to human DNA, supporting optimal cellular response and long-term safety. The salmon are free from antibiotics, antiparasitics and artificial feed. MSC-certified sustainable fishing ensures traceability and responsible sourcing, while the molecules are extracted and purified without unnecessary additives.

Treatment Areas for Ameela Polynucleotides

Ameela Polynucleotide injections can be used across multiple areas to improve skin quality, hydration and elasticity. Common treatment areas include the face, under-eye area (periocular region), neck, décolletage, hands, and scalp. The treatment is especially effective in delicate or ageing-prone areas, where skin appears thinner, dull or less supported.

Key Benefits of Ameela Polynucleotide Treatment

• Improves skin firmness, elasticity and tone for a smoother, more refined appearance

• Softens fine lines and visible signs of ageing while maintaining natural expression

• Deeply hydrates and comforts the skin, supporting post-procedure recovery

• Reduces puffiness and dark under-eye circles, creating a brighter, more refreshed look

• Smooths texture and hollowing in delicate areas, including the eye contour

• Provides antioxidant protection against environmental stress and premature ageing

• High-concentration polynucleotide (PN) formula for enhanced regenerative performance

• Supports healthy skin and scalp quality, helping maintain overall vitality

Stylage Hydromax is an advanced hyaluronic acid skinbooster treatment offered at The Grange Clinic designed to significantly improve overall skin quality from the inside out. Using a unique combination of cross-linked and free hyaluronic acid with a sorbitol-enriched buffer, this injectable gel delivers deep hydration while supporting the skin’s natural regenerative processes. 

The exclusive Skin3 Complex works on multiple layers of the skin to stimulate collagen and elastin production, promote cell regeneration, and strengthen the skin’s barrier function, resulting in smoother, more radiant and resilient skin with limited recovery time.

Stylage Hydromax is ideal for those seeking to enhance skin texture and elasticity, boost hydration, and reduce the visible signs of ageing without invasive procedures. Suitable for areas such as the face, neck and décolletage, this treatment helps restore a youthful glow and improve moisture retention, while encouraging a healthier overall skin structure. Patients often notice natural-looking, long-lasting results that contribute to a refreshed, revitalised appearance.

Sculptra is a collagen‑stimulating injectable treatment that works with your body’s natural processes to restore firmer, smoother and more youthful‑looking skin. Unlike traditional dermal fillers that simply add volume, Sculptra uses poly‑L‑lactic acid (PLLA) to stimulate your own collagen production over time, helping to improve skin quality and reduce the visible signs of ageing with natural‑looking results.

At The Grange Clinic, Sculptra is ideal for patients seeking long‑lasting rejuvenation, subtle facial contouring and enhanced structural support. It can improve volume loss, soften deep lines and wrinkles, and enhance the overall texture and elasticity of the skin, gradually revealing a refreshed and revitalised appearance. Results develop over weeks to months as your collagen rebuilds, offering enduring improvements that feel natural and balanced.